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FR180204
Chemical Information
M.Wt
327.34
Storage
Please store the product under the reco...
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AZD4547
Description of:AZD4547
FGFR inhibitor AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal trans...
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MDV3100(Enzalutamide)
Description of:MDV3100(Enzalutamide)
MDV3100 has approximately fivefold higher binding affinity for the androgen receptor (AR) compared to the ...
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TAK875
Description of:TAK875
TAK-875 was eliminated slowly with a mean terminal elimination tfrac12 of approximately 28.1 to 36.6 hours. Systemic expo...
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AMG900
Description of:AMG 900
AMG 900 repressed autophosphorylation of aurorakinases A and B as well as the phosphorylation of histone H3.The predomin...
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Pomalidomide(CC-4047)
Description of:Pomalidomide
Pomalidomide is tumor necrosis factor-α inhibitor and a new immunomodulator with an IC50 of 1 μM
Theore...
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YM155
Description of:YM155
YM155, a novel small molecule survivin inhibitor, suppressed expression of survivin and induced apoptosis in PC-3 and PPC-...
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Serdemetan(JNJ 26854165)
Description of:Serdemetan
Serdemetan(JNJ 26854165) is an orally bioavailable, first-in-class small-molecule HDM2 antagonist with potential anti...
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Nutlin-3
Description of:Nutlin-3
Nutlin-3 is a MDM-2 antagonist with an IC50 of 90 nM. It induces the expression of p53-regulated genes and exhibits pot...
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Nutlin-3a (chiral)
Description of:Nutlin-3a (chiral)
Nutlin-3 is MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p53...
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ABT-737/ABT737
Description of:ABT-737
ABT-737 induces Bax conformational change but fails to activate Bak or trigger Bax translocation. Coadministration of ro...
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TW-37
Description of:TW-37
TW-37 is Bcl-2 inhibitor (Ki values are 0.29 μM and 1.11 μM for Bcl-2 and Bcl-XL respectively). TW-37 inhibits the a...
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Antibody-drug Conjugate/ADC Related
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