Chemren Bio-Engineering Co., Ltd.

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Neuronal Signaling

LRRK2
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Membrane Transporter/Ion Channel

P-glycoprotein
TRP Channel
Proton Pump
Na+/K+ ATPase
GABA Receptor
Sodium Channel
Apoptosis inducer
VDAC
CFTR
Potassium Channel
AMPAR
URAT1
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Aurora/Ksp

Aurora B
Ksp
Aurora A
Aurora
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Chromatin/Epigenetics

Pim
Bromodomain
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Apoptosis

Apoptosis inducer
PKD
IAP
TNF-alpha
survivin suppressant
Caspase
p53
MDM-2 antagonist
Bcl-2
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GPCR

LPL Receptor
Adenosine Receptor
mAChR
OX Receptor
Sigma Receptor
mGluR2
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Hormone

SARM
GPR
GPR40
Androgen Receptor
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Ion channel

ICB
potassium channel
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MAPK

RSK
MNK
BMK1
ERK
MEK
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PARP

PARP
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PI3K/Akt/mTOR

AMPK
CK2
Akt
ATM
DNA-PK
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HDAC

HDAC
HDAC6
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Neuro Signaling

LRRK2
Amyloid β
Dopamine Receptor
COX-2
CGRP
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Jak/Stat

Pim
EGFR
JAK3
JAK
JAK2
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Integrase/CCR5

CCR5
HIV integrase
HIV-1 integrase
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Receptor Tyrosine Kinases

BtK
TrkA
ALK
c-ABL
c-Kit
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Proteases/HSP90/HSP70

HSP
MMP
DPP-4
Calpains
HSP-90
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TGF-beta/Smad Signaling

TGF-βR
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Ca/cAMP/Lipid Signaling

PKC
PIM
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Cell Cycle/Checkpoint

Cdc42
DNA Damage
Cyclin-Dependent Kinases
Aurora Kinase
Deubiquitinase
CRM1
Telomerase
Sirtuin
Chk 1
HMTase
Histone acetyltransferases(HATs)
PLK
EZH2
E1 enzyme
Bcr-Abl
ATR
p97
BET bromodomain
Mps1
DNMT
PERK
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Wnt/Hedgehog/Notch

β-catenin
Notch
CK1
Smo
γ-secretase
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Cell Metabolism

PDE
IDO
Dopamine β-hydroxylase
Cytochrome P450
Phosphodiesterases (PDEs)
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7-TM Receptors

5-HT Receptors
Opioid Receptors
Metabotropic glutamate receptors
Smoothened Receptors
G Protein
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Intermediates

Intermediates

inhibitor

inhibitor