Chemren Bio-Engineering Co., Ltd.

Product name : Nutlin-3
Item : CR1007
CAS : 548472-68-0
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Description of:Nutlin-3
Nutlin-3 is a MDM-2 antagonist with an IC50 of 90 nM. It induces the expression of p53-regulated genes and exhibits potent antiproliferative activity in cells with functional p53, but not in cells with mutated p53. Nutlin-3 also inhibits the growth of human tumor xenografts in nude mice by 90% at a dose of 200 mg/kg.

Theoretical analysis:Nutlin-3
M.Wt: 581.5
Formula: C30H30Cl2N4O4
Solubility: DMSO
Purity: 99%
CAS No: 548472-68-0
Storage: at -20℃ 2 years

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Quality control data:
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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