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Products > Apoptosis > Bcl-2 > ABT-737/ABT737
Product name : ABT-737/ABT737
Item : CR1005
CAS : 852808-04-9
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Details:
Description of:ABT-737
ABT-737 induces Bax conformational change but fails to activate Bak or trigger Bax translocation. Coadministration of roscovitine and ABT-737 untethers Bak from Mcl-1 and Bcl-xL, respectively, triggering Bak activation and Bax translocation.

Theoretical analysis:ABT-737
M.Wt: 813.43
Formula: C42H45ClN6O5S2
Solubility: 10 mmol/L in DMSO
Purity: 99%
Storage: at -20C 2 years
Appearance:yellow solid
CAS No: 852808-04-9

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