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Pazopanib(GW-786034)
Description of:Pazopanib(GW-786034)
Pazopanib: a novel multitargeted tyrosine kinase Inhibitor.
Theoretical analysis:Pazopanib(G...
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BAY 61-3606
Description of:BAY 61-3606
BAY 61-3606 (BAY 61-3606) is a cell-permeable imidazopyrimidine compound that acts as a potent, ATP-competitive, rev...
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R788
Description of:R788
R935788 (Fostamatinib disodium) has shown clinical activity in heavily pre-treated NHL and CLL patients, exhibits inhibitor...
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Bafetinib
Description of:Bafetinib
Bafetinib (INNO-406) is an orally available, dual Abl/Lyn kinase inhibitor (cell IC50 : 11 ~ 22 nM).
Theoreti...
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Fingolimod(FTY720)
Description of:Fingolimod(FTY720)
Fingolimod is Src-bcr-Abl Inhibitor & S1P receptor agonist with IC50 of 0.137, 10.98 nM for (S)- and (R)-...
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Saracatinib
Description of:Saracatinib
AZD0530 inhibited tumor growth in a manner independent of dose and inhibited phosphorylation of Focal adhesion kinas...
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Dasatinib
Description of:Dasatinib
Dasatinib is a multikinase inhibitor with potent activity against BCR?CABL kinase (IC50 <1 nM) and SFKs (IC50 of 0....
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Danusertib(PHA-739358)
Description of:Danusertib(PHA-739358)
PHA-739358 is a pyrrolo-pyrazole, which inhibits Aurora kinases in a biochemical assay with IC50s of 13, ...
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Bosutinib(SKI-606)
Description of:Bosutinib(SKI-606)
Bosutinib is Src family kinase inhibitor. Bosutinib inhibited migration of breast cancer cell lines with IC50...
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Crenolanib (CP-868569)
Description of:Crenolanib (CP-868569)
Crenolanib (CP-868569) is a highly selective and potent PDGFR-α inhibitor with IC50 of 0.9 and 1.8 ...
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Neuronal Signaling
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