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BMS-599626
Description of:BMS-599626
BMS-599626 (BMS-599626; AC480) is a highly selective pan-HERKinase inhibitor with IC50 of 20 and 30 nM for the inhibi...
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WZ3146
Description of:WZ3146
WZ3146 has a basic chemical framework (covalent pyrimidine) which is different from that of other EGFR inhibitors.This ag...
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WZ4002
Description of:WZ4002
WZ4002 has a basic chemical framework (covalent pyrimidine) which is different from that of other EGFR inhibitors. [1]More>>
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WZ8040
Description of:WZ8040
WZ8040 is an irreversiblely inhibitor against EGFR T790M (mutation of the gatekeeper T790 residue) which is detected in 5...
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PF299804
Description of:PF299804
PF299804 is a quinazalone-based irreversible pan-ERBB inhibitor structurally related to CI-1033. PF299804 is a potent i...
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PD153035
Description of:PD153035
An extremely potent inhibitor of epidermal growth factor (EGF) receptor tyrosine kinase, with an IC50 of 25 pM. Inhibit...
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Pelitinib(EKB-569)
Description of:Pelitinib(EKB-569)
Pelitinib is a 3-cyanoquinoline pan-ErbB tyrosine kinase inhibitor with potential antineoplastic activity. Pe...
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Neratinib(HKI-272)
Description of:Neratinib(HKI-272)
Neratinib binds to the HER-2 receptor irreversibly, thereby reducing autophosphorylation in cells, apparently...
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Lapatinib
Description of:Lapatinib
Lapatinib (GW572016) is a selective inhibitor of both epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinas...
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Neuronal Signaling
BtK
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