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Tandutinib
Description of:Tandutinib
Tandutinib (MLN518) is a FLT3 inhibitor. In cell-based assays Tandutinib inhibited FLT3 ,PDGFR, and KIT with IC50 val...
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KW2449
Description of:KW2449
KW-2449 potently and selectively inhibits the growth of leukemia cells harboring constitutively activated FLT3 kinase bot...
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AC220
Description of:AC220
AC220 exhibits low nanomolar potency in biochemical and cellular assays and exceptional kinase selectivity, and in animal ...
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Linifanib
Description of:Linifanib
The kinase inhibition profile of ABT-869 is evident in cellular assays of RTK phosphorylation (IC50 values of 2, 4 and...
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Danusertib(PHA-739358)
Description of:Danusertib(PHA-739358)
PHA-739358 is a pyrrolo-pyrazole, which inhibits Aurora kinases in a biochemical assay with IC50s of 13, ...
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AP24534(Ponatinib)
Description of:AP24534(Ponatinib)
AP24534 is a novel potent, orally available small molecule multitargeted kinase inhibitor with IC50 of 0.37, ...
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BGJ398
Description of:BGJ398
BGJ398 is a pan FGFR kinase inhibitor, and BGJ398 is an orally bioavailable pan inhibitor of human fibroblast g...
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BIBF-1120
Description of:BIBF-1120
BIBF-1120 (Vargatef) is an inhibitor of VEGFR, PDGFR and FGFR. all three VEGFR subtypes (IC50=13–34nmol/L) , PDG...
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Ambrisentan
Description of:Ambrisentan
Ambrisentan is an endothelin receptor type A-selective endothelin receptor antagonist. Ambrisentan is useful for pul...
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Sitaxsentan sodium
Description of:Sitaxsentan sodium
Sitaxsentan sodium (TBC11251 sodium salt) is an orally active, highly selective antagonist of endothelin A re...
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Neuronal Signaling
BtK
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