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CI1040
Description of:CI1040
CI-1040 is a selective MEK inhibitor (Ki = 300 nM in vitro). CI-1040 suppresses FGF-mediated angiogenesis in vivo and dec...
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AZD6244
Description of:AZD6244
AZD6244 potently down-regulated the levels of phospho-ERK1/2 and its downstream effector, p-p70S6K, in the MV4-11 and MO...
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GSK1120212
Description of:GSK1120212-Trametinib
MEK inhibitor GSK1120212 specifically binds to and inhibits MEK 1 and 2, resulting in an inhibition of gro...
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PD0325901
Description of:PD0325901
PD0325901 is roughly 500-fold more potent than CI-1040 with respect to its cellular effects on phosphorylation o...
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Chromatin/Epigenetics
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