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Products > MAPK > MEK > PD0325901
Product name : PD0325901
Item : CR1044
CAS : 391210-10-9
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Details:
Description of:PD0325901
 PD0325901 is roughly 500-fold more potent than CI-1040 with respect to its cellular effects on phosphorylation of ERK1 and ERK2, exhibiting subnanomolar activity.
PD0325901 inhibits MEK activity in mouse colon 26 cells (IC50 = 0.33 nM). PD0325901 inhibits the growth of melanoma cell lines in vitro and in vivo; induces G1-phase cell cycle arrest and apoptosis in a mouse xenograft model. 

Theoretical analysis:PD0325901
M.Wt: 482.19
Formula: C16H14F3IN2O4
Solubility: DMSO
Purity: 98%
Storage: at -20℃ 2 years
CAS No: 391210-10-9

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