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Sorafenib Tosylate(Nexavar)
Description of:Sorafenib Tosylate
Sorafenib (Bay 43-9006) is a novel bi-aryl urea compound that inhibits cell proliferation by targeting the ER...
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PLX-4720
Description of:PLX-4720
PLX4720 preferentially inhibits the active B-RafV600E kinase compared with a broad spectrum of other kinases and potent...
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MEK162
Description of:MEK162
MEK162(ARRY-162; ARRY-438162) is an oral, highly selective MEK inhibitor. MEK162(ARRY-162; ARRY-438162) is now being inve...
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GDC-0973
Description of:GDC-0973
GDC-0973 is also known as mitogen activated protein kinase kinase (MAPKK), is a key component of the RAS/RAF/MEK/ERK pa...
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BMS777607
Description of:BMS777607
BMS 777607 is a Small-Molecule Met Kinase Inhibitor with an IC50 of < 0.1 μM.
Theoretical analysis:BMS7...
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PD318088
Description of:PD318088
The MEK1 inhibitor PD318088 binds simultaneously with ATP in a region of the kinase active site that is adjacent to the...
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AZD8330
Description of:AZD8330
AZD8330 (RRY-424704，ARRY-704) specifically inhibits mitogen- activated protein kinase kinase 1 (MEK or MAP/ERK kinase1),...
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BIX02188
Description of:BIX02188
BIX02188 is a MEK5-selective inhibitor with an IC50 of 0.8 ± 1.0 μM.
Theoretical analysis:BIX02188More>>
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Pimasertib(AS703026)
Description of:AS703026
AS703026 inhibited growth and survival of MM cells (cell IC50 ranging from 0.005 to 2 µM) and cytokine-indu...
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PD98059
Description of:PD98059
PD98059 is inhibitor of mitogen-activated protein kinase kinase (MAPKK / MEK). PD98059 acts by binding to the inac...
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