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Vinorelbine(Navelbine)
Description of:Vinorelbine(Navelbine)
Vinorelbine (Navelbine) is the first 5´NOR semi-synthetic vinca alkaloid and exerts its activ...
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SB203580
Description of:SB203580
SB 203580 is a potent inhibitor of LPS-induced cytokine synthesis in the human monocyte cell line THP-1 (IC50 = 50-100 ...
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LY2228820
Description of:LY2228820
LY2228820 is a novel and potent p38MAPK inhibitor: in vitro kinase enzyme activity showed that the IC50 for p38α...
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CC-401
Description of:CC-401
CC-401 competitively binds the ATP binding site of JNK, resulting in inhibition of the phosphorylation of the N-ter...
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AS 602801
Description of:AS 602801
AS 602801(Bentamapimod) is a novel, orally active, Jun Kinase Inhibitor (JNK-I AS602801)
Theoretical analysis...
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AZ 628
Description of:AZ 628
AZ 628 is a selective RAF inhibitor. AZ 628 shows strong selectivity for RAF kinases among a panel of 150 tested kinases;...
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GW 5074
Description of:GW 5074
GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor (IC50 = 9 nM). GW 5074 displays ≥ 100-fold ...
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PLX-4032(RG7204)
Description of:PLX-4032(RG7204)
PLX4032 is a highly selective inhibitor of BRAF kinase activity, with an IC50 of 44 nmol/L against V600E-mutant...
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SB590885(GSK2118436)
Description of:SB590885(GSK2118436)
B-590885 is a novel, potent and selective small molecule B-Raf kinase inhibitor with a Ki app of 0.16 &plus...
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GDC-0879
Description of:GDC-0879
GDC-0879 is a highly selective, novel potent, orally bioavailable B-Raf inhibitor in various in vitro and cell-based as...
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