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NSC 74859
Description of:NSC 74859
S31-201 (NSC 74859) is a chemical probe inhibitor of Stat3 activity, which was identified from the National Cancer Ins...
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AZD1480
Description of:AZD1480
AZD1480 suppresses the growth of human solid tumor xenografts harboring persistent Stat3 activity. [1] AZD1480 inhibited...
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TG101348
Description of:TG101348
TG-101348 is a potent, highly selective and ATP- competitive JAK2 inhibitor with an IC50 of 3 nM for JAK2 and JAK2 V617...
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TG101209
Description of:TG101209
TG101209, an orally bioavailable small molecule that potently inhibits JAK2 (IC50=6 nM), FLT3 (IC50=25 nM) and RET (IC5...
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CYT387
Description of:CYT387
CYT387 has significantly less activity against other kinases, including JAK3 (IC50=0.16 μM). CYT387 inhibits growth of...
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LY2784544
Description of:LY2784544
LY2784544 is a small molecule selective mutant JAK2 kinase inhibitor with an IC50 of 68 nM.
Theoretical analy...
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Ruxolitinib(INCB018424)
Description of:Ruxolitinib(INCB018424)
INCB018424 (Ruxolitinib) is an orally bioavailable JAK inhibitor .(IC50 values for JAK1, JAK2 and JAK3 a...
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Tasocitinib(CP690550)
Description of:Tasocitinib(CP690550)
CP690550(Tasocitinib) treatment of murine factor-dependent cell Patersen-erythropoietin receptor (FDCP-Epo...
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Neuronal Signaling
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