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Antibody-drug Conjugate/ADC Related
Trk Receptor
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Product name : INCB28060
Item : CRG105
CAS : 1029712-80-8
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| Details: |
Description of:INCB28060
Oral dosing of INCB28060 results in time- and dose-dependent inhibition of c-MET phosphorylation and tumor growth in c-MET-driven mouse tumor models, and the inhibitor is well tolerated at doses that achieve complete tumor inhibition. In a further exploration of potential interactions between c-MET and other signaling pathways, we found that activated c-MET positively regulates the activity of epidermal growth factor receptors (EGFR) and HER-3, as well as expression of their ligands. These effects are reversed with INCB28060 treatment. Theoretical analysis:INCB28060 CAS No：1029712-80-8 Formula：C23H17FN6O M.Wt：412.42 Purity：98％ Availability and price:INCB28060 Pakage：25mg/50mg/100mg/250mg/500mg/1g/5g Stock : in stock We offer significant discount for larger quantity order. For quotation, question, and order, please send email to : sales@chemrenpharm.com Quality control data: Quality Control by H-NMR,C-NMR,LC-MS,HPLC. Product will be shipped with supporting analytical data. Fast delivery about 4-5 working days |
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