Chemical Information
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CAS No.
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1005504-62-0 |
Formula |
C21H23Cl2N5O |
M.Wt |
432.35 |
Synonyms |
RG 3039; RG-3039; PF-06687859; PF 06687859; PF06687859 |
Smiles code |
NC1=NC(N)=C2C(OCC3CCN(CC4=C(Cl)C=CC=C4Cl)CC3)=CC=CC2=N1.[H]Cl.[H]Cl |
Chemical Name |
5-((1-(2,6-dichlorobenzyl)piperidin-4-yl)methoxy)quinazoline-2,4-diamine |
Technical Data
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Appearance |
Solid powder |
Purity |
97% |
Solubility |
Soluble in DMSO |
Storage |
-20 ℃ for 3 years |
Shipping condition |
Shipped under ambient temperature |
Quality control |
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Remarks
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RG3039 is a potent DcpS inhibitor, which can improve motor function in SMA mice. RG3039 also showed activity to improve survival, function and motor unit pathologies in two SMA mouse models. |
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Stock : in stock
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