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Product name : RG3039
Item : CR1092
CAS : 1005504-62-0
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Details:

Chemical Information

CAS No. 
 
1005504-62-0
Formula C21H23Cl2N5O 
M.Wt 432.35 
Synonyms RG 3039; RG-3039; PF-06687859; PF 06687859; PF06687859 
Smiles code NC1=NC(N)=C2C(OCC3CCN(CC4=C(Cl)C=CC=C4Cl)CC3)=CC=CC2=N1.[H]Cl.[H]Cl 
Chemical Name 5-((1-(2,6-dichlorobenzyl)piperidin-4-yl)methoxy)quinazoline-2,4-diamine 

Technical Data

Appearance Solid powder 
Purity 97% 
Solubility Soluble in DMSO 
Storage -20 ℃ for 3 years 
Shipping condition Shipped under ambient temperature 
Quality control  

Remarks

RG3039 is a potent DcpS inhibitor, which can improve motor function in SMA mice. RG3039 also showed activity to improve survival, function and motor unit pathologies in two SMA mouse models. 

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