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Vatalanib Dihydrochloride
Description of:Vatalanib Dihydrochloride
Vatalanib is a potent, selective, orally active inhibitor of the VEGFR tyrosine kinases VEGFR-1 (Flt-1...
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CP-673451
Description of:CP-673451
In a sponge angiogenesis model, CP-673451 inhibited 70% of PDGF-BB-stimulated angiogenesis at a dose of 3 mg/kg ...
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KRN633
Description of:KRN633
KRN633 inhibits PDGFR-α and c-Kit at higher concentrations only (IC50 = 0.97 µM and 4.33 µM, respective...
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Cabozantinib
Description of:Cabozantinib
Cabozantinib was granted orphan-drug status by the FDA in January 2011.It is currently in a number of clinical tria...
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Pazopanib(GW-786034)
Description of:Pazopanib(GW-786034)
Pazopanib: a novel multitargeted tyrosine kinase Inhibitor.
Theoretical analysis:Pazopanib(G...
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Neuronal Signaling
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