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PCI-32765
Description of:PCI-32765
PCI-32765 is highly active and well tolerated in CLL/SLL pts irrespective of high risk genomic abnormalities. Although...
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SB-431542
Description of:SB-431542
SB-431542 is potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor acti...
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AEE788
Description of:AEE788
AEE788 demonstrated antiproliferative activity against a range of EGFR and ErbB2-overexpressing cell lines and inhibited ...
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OSI930
Description of:OSI 930
OSI-930 is designed to target both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors.<...
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Cediranib(AZD2171)
Description of:Cediranib (AZD2171)
Cediranib (AZD2171) is a once-daily oral tyrosine kinase inhibitor that targets vascular endothelial growth ...
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MP470
Description of:MP470
MP470 reduced c-Met phosphorylation and enhanced radiation-induced cell kill by 0.4 logs in SF767 cells. Cells pretr...
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Motesanib Diphosphate
Description of:Motesanib Diphosphate
Motesanib Diphosphate potently inhibited VEGF-induced but not bFGF-induced proliferation of HUVECs with IC...
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RAF265(CHIR-265)
Description of:RAF265(CHIR-265)
RAF is a key component of the RAS/RAF/MEK/ERK signal-transduction pathway, which controls cell proliferation, d...
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Sunitinib Malate(SU 11248)
Description of:Sunitinib Malate(SU 11248)
Sunitinib dose-dependently inhibited stem cell factor (SCF)-induced phosphotyrosine levels on KIT (IC...
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PD173074
Description of:PD173074
PD173074 is a potent ATP-competitive, reversible FGFR and VEGFR inhibitor with IC50 of 5, 21.5 and ~100 nM for FGFR3, F...
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