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CUDC-101
Description of:CUDC-101
This drug has novel structure incorporating HDAC inhibitory functionality into the pharmacophore of the EGFR and ...
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Afatinib
Description of:Afatinib
Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.
Theor...
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BMS690514
Description of:BMS690514
BMS-690514 is currently under investigation as an oral agent for the treatment of solid tumors. In vitro and in vivo s...
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AG-490
Description of:AG-490
AG490 inhibits the proliferation of several cell types including leukemia cells and fibroblasts. AG490 is also selective ...
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Foretinib(GSK1363089)
Description of:Foretinib(GSK1363089)
GSK1363089 (XL880)is an orally bioavailable，small molecule MET/VEGFR2 inhibitor with potential antineoplas...
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MGCD-265
Description of:MGCD-265
MGCD265 is a tyrosine kinase inhibitor that targets the MET, VEGFR-1, VEGFR-2, VEGFR-3, RON and TIE2 receptor tyrosine ...
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PHA-665752
Description of:PHA-665752
M.Wt:641.61
Formula:C32H34Cl2N4O4S
Solubility:Soluble to 100 mM in DMSO
Purity:>98 %
S...
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SU-11274
Description of:SU-11274
SU11274 is a highly specific inhibitor of c-Met , with in vitro IC50 for the Met enzyme at 0.012 umol/L.
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SGX523
Description of:SGX523
SGX-523, an orally bioavailable small molecule, specifically binds to c-Met protein, or hepatocyte growth factor receptor...
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AMG208
Description of:AMG208
AMG 208 is a small molecule inhibitor of c-Met, which inhibits both ligand-dependent and ligand-independent c-Met activat...
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Neuronal Signaling
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