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SNX5422
Description of:SNX5422
PF-04929113 (SNX-5422) is a synthetic prodrug targeting the human heat-shock protein 90 (Hsp90) with potential antineopl...
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MPC3100
Description of:MPC3100
MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of heat shock protein 90 (Hs...
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17-AAG(Tanespimycin)
Description of:17-AAG(Tanespimycin)
17AAG is a less toxic analogue of the geldanamycin which binds to Hsp90 (Heat Shock Protein 90) and alters ...
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BIIB021
Description of:BIIB021
In tumor cells, BIIB021 induced the degradation of Hsp90 client proteins (including HER-2, AKT, and Raf-1) and up-regula...
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SNX-2112
Description of:SNX-2112
SNX-2112 is an active metabolite of the compounds SNX-5542. SNX-2112 is rapidly transformed form SNX-5542 after adminis...
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NVP-AUY922
Description of:NVP-AUY922
NVP-AUY922, a novel resorcinylic isoxazole amide heat shock protein 90 (HSP90) inhibitor. NVP-AUY922 potently inhibit...
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NVP-BEP800
Description of:NVP-BEP800
NVP-BEP800 is a novel, fully synthetic, oral Hsp90 inhibitor with an IC50 of 0.058 ± 0.006 μM.
The...
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Geldanamycin
Description of:Geldanamycin
Geldanamycin,Binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity. Consequently inhi...
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Neuronal Signaling
HSP
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