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Antibody-drug Conjugate/ADC Related
AMPK
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Product name : PF-04691502
Item : CRV902
CAS : 1013101-36-4
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| Details: |
Description of:PF 04691502
PF-04691502 is an ATP-competitive inhibitor which potently inhibits recombinant class I PI3K and mTOR in biochemical assays and suppresses transformation of avian fibroblasts mediated by wild type PI3K��, ��or mutant PI3K��.PF-04691502 has potential antineoplastic activity. In PIK3CA-mutant and PTEN-deleted cancer cell lines, PF-04691502 decreases phosphorylation of AKT T308 and AKT S473 with IC50 ranging from 7.5 to 47 nM and from 3.8 to 20 nM respectively, and inhibits cell proliferation with IC50 ranging from 179 to 313 nM. Theoretical analysis:PF 04691502 CAS NO: 1013101-36-4 Molecular Formula: C22H27N5O4 Molecular Weight: 425.48 Purity: 98% min Solubility: In DMSO Storage: -20°C Availability and price:PF 04691502 Pakage：25mg/50mg/100mg/250mg/500mg/1g/5g Stock : in stock We offer significant discount for larger quantity order. For quotation, question, and order, please send email to : sales@chemrenpharm.com Quality control data: Quality Control by H-NMR,C-NMR,LC-MS,HPLC. Product will be shipped with supporting analytical data. Fast delivery about 4-5 working days |
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