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LY411575
Description of:LY411575
LY411575 is a selective, cell permeable, small molecule gamma secretase inhibitor with an IC50 of 0.1 nM for APP23 and ...
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DAPT
Description of:DAPT
DAPT is inhibitor of γ-secretase. DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal...
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RO4929097
Description of:RO4929097
RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM.
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MK-0752
Description of:MK-0752
MK-0752 is a potent gamma secretase (γ-secretase) inhibitor in clinical development with an IC50 of 5 nM for A&bet...
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E 2012
Description of:E 2012
E 2012 is γ-secretase inhibitor.
Theoretical analysis:E 2012
M.Wt: 419.5
Formula: C25H26FN3O...
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Semagacestat(LY450139)
Description of:Semagacestat(LY450139)
Semagacestat (LY450139) is a γ-secretase blocker with an IC50 of 15 nM. In treatment of Alzheimer's...
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Neuronal Signaling
β-catenin
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