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KU 0063794
Description of:KU 0063794
KU-0063794 displays no activity at PI 3-kinase or 76 other kinases tested. Inhibits activation and hydrophobic motif ...
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Deforolimus(MK-8669)
Description of:Deforolimus(MK-8669)
Deforolimus (Ridaforolimus) is a small-molecule inhibitor of mTOR.
Theoretical analysis:Deforolimu...
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Temsirolimus
Description of:Temsirolimus
Temsirolimus has shown promising preclinical and early clinical antitumor activity and is currently in phase III cl...
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TWS119
Description of:TWS119
TWS119 is inhibitor of glycogen synthase kinase-3β (IC50 = 30 nM). TWS119 induces neuronal differentiation in plurip...
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SB 216763
Description of:SB 216763
SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3�� with an IC50 value of 34 nM (si...
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CHIR99021(CT99021)
Description of:CHIR99021(CT99021)
CHIR-99021(CT99021) is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative a...
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KU57788(NU7441)
Description of:KU57788(NU7441)
NU 7441(KU 57788) is a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (IC50 values are 14,...
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CP466722
Description of:CP466722
CP-466722 is non-toxic and does not inhibit PI3K or PI3K-like protein kinase family members in cells. CP-466722 i...
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KU55933
Description of:KU55933
Exposure of cells to KU-55933 resulted in a significant sensitization to the cytotoxic effects of ionizing radiation and...
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KU-60019
Description of:KU-60019
As expected, KU-60019 is a highly effective radiosensitizer of human glioma cells. A-T fibroblasts were not radiosensit...
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