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Description of:WYE 125132
WYE-132 inhibited mTORC1 and mTORC2 in diverse cancer models in vitro and in vivo. Importantly,consistent with genetic ablation of mTORC2, WYE-132 targeted P-AKT(S473) and AKT function without significantly reducing the steady-state level of the PI3K/PDK1 activity biomarker P-AKT(T308), highlighting a prominent and direct regulation of AKT by mTORC2 in cancer cells. Theoretical analysis:WYE 125132 M.Wt: 519.6 Formula: C27H33N7O4 Solubility: DMSO Purity: >98% Storage: -20°C for 2 years CAS No: 1144068-46-1 Availability and price:WYE 125132 Pakage:250mg/500mg/1g/5g We offer significant discount for larger quantity order. For quotation, question, and order, please send email to : sales@chemrenpharm.com Quality control data: Quality Control by H-NMR,C-NMR,LC-MS,HPLC. Product will be shipped with supporting analytical data. Fast delivery about 4-5 working days |
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