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Description of:AZD8055
In vitro, AZD8055 potently inhibits proliferation and induces autophagy in H838 and A549 cells.In vivo, AZD8055 induces a dose-dependent pharmacodynamic effect on phosphorylated S6 and phosphorylated AKT at plasma concentrations leading to tumor growth inhibition. It inhibits the phosphorylation of mTORC1 substrates p70S6K and 4E-BP1 as well as phosphorylation of the mTORC2 substrate AKT and downstream proteins. Theoretical analysis:AZD8055 M.Wt: 465.54 Formula: C25H31N5O4 Solubility: Soluble in DMSO Purity: >99% Storage: at -20℃ 2 years CAS No: 1009298-09-2 Availability and price:AZD8055 Pakage:250mg/500mg/1g/5g We offer significant discount for larger quantity order. For quotation, question, and order, please send email to : sales@chemrenpharm.com Quality control data: Quality Control by H-NMR,C-NMR,LC-MS,HPLC. Product will be shipped with supporting analytical data. Fast delivery about 4-5 working days 备注: 若要询价或订购,请打销售电话咨询:0519-85788828,或加QQ:2500035664咨询,量大从优,我们会尽快回复。 注意事项:本产品是化学试剂,仅供实验室使用 |
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