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CYC116
Description of:CYC116
CYC116 inhibits Aurora kinases A and B and VEGFR2, resulting in disruption of the cell cycle, rapid cell death, and the i...
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ENMD-2076
Description of:ENMD-2076
ENMD-2076 is a antiangiogenic and Aurora kinase inhibitor with IC50 of 3, 13, 350, 23, 40, 93 and 120 nM for Flt-3, Au...
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CCT129202
Description of:CCT129202
CCT129202 causes the accumulation of human tumor cells with ��4N DNA content, leading to apoptosis. The results showed...
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MLN8237(Alisertib)
Description of:MLN8237
Alisertib is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the Aurora A k...
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SNS-314
Description of:SNS-314
SNS-314 is inhibitor of Aurora kinases A(IC50=9.0nM), B(IC50=31nM), and C(IC50=3.4nM).
Theoretical analysis:SNS...
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Hesperadin
Description of:Hesperadin
Hesperadin causes this phenotype by inhibiting the function of the mitotic kinase Aurora B. Hesperadin is a human Aur...
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GSK1070916
Description of:GSK1070916
GSK1070916 displays dose-dependent inhibition of phosphorylation of an Aurora B–specific substrate in mice and ...
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JNJ-7706621
Description of:JNJ-7706621
JNJ-7706621 slowed the growth of cells and at higher concentrations induced cytotoxicity. Inhibition of CDK1 kinase ...
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MLN8054
Description of:MLN8054
Human tumor cells treated with MLN8054 show a high incidence of abnormal mitotic spindles, often with unseparated centro...
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PHA-680632
Description of:PHA-680632
PHA-680632 is active on a wide range of cancer cell lines and shows significant tumor growth inhibition in different ...
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Antibody-drug Conjugate/ADC Related
Aurora B
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