常州市存仁生物工程有限公司

产品 > Aurora/Ksp > Aurora > MLN8054
产品名称 : MLN8054
型号 : CR1016
CAS : 869363-13-3
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产品详细:
Description of:MLN8054
Human tumor cells treated with MLN8054 show a high incidence of abnormal mitotic spindles, often with unseparated centrosomes.Auora kinase inhibitor MLN8054 binds to and inhibits Aurora kinase A, resulting in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregration, and inhibition of cell proliferation.MLN8054-treated cells frequently show alignment defects during metaphase, lagging chromosomes in anaphase, and chromatin bridges during telophase. 

Theoretical analysis:MLN8054
M.Wt:  476.86
Formula:  C25H15ClF2N4O2
Solubility:  Soluble in DMSO
Purity:  >99%
Storage:  -20C 2 years
CAS No:  869363-13-3 

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Quality control data:
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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