产品分类
Antibody-drug Conjugate/ADC Related
Aurora B
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| 产品详细: |
Description of:MLN8054
Human tumor cells treated with MLN8054 show a high incidence of abnormal mitotic spindles, often with unseparated centrosomes.Auora kinase inhibitor MLN8054 binds to and inhibits Aurora kinase A, resulting in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregration, and inhibition of cell proliferation.MLN8054-treated cells frequently show alignment defects during metaphase, lagging chromosomes in anaphase, and chromatin bridges during telophase. Theoretical analysis:MLN8054 M.Wt: 476.86 Formula: C25H15ClF2N4O2 Solubility: Soluble in DMSO Purity: >99% Storage: -20C 2 years CAS No: 869363-13-3 Availability and price: We offer significant discount for larger quantity order. For quotation, question, and order, please send email to : sales@chemrenpharm.com Quality control data: Quality Control by H-NMR,C-NMR,LC-MS,HPLC. Product will be shipped with supporting analytical data. Fast delivery about 4-5 working days |
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