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VX745
Description of:VX745
In vitro, VX-745 was selective for p38 MAPK compared to a large panel of kinases (IC50≥20µM). VX-745 selectively ...
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TAK715
Description of:TAK715
TAK-715 is a inhibitor of p38 MAPK (IC50 = 7.1 nM for p38 MAPKα). TAK-715 also inhibits Wnt-3a-stimulated β-ca...
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SB 202190
Description of:SB 202190
SB202190 is a highly selective, potent and cell-permeable inhibitor of p38 MAP kinase. SB202190 binds within the ATP p...
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Vinorelbine(Navelbine)
Description of:Vinorelbine(Navelbine)
Vinorelbine (Navelbine) is the first 5´NOR semi-synthetic vinca alkaloid and exerts its activ...
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SB203580
Description of:SB203580
SB 203580 is a potent inhibitor of LPS-induced cytokine synthesis in the human monocyte cell line THP-1 (IC50 = 50-100 ...
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LY2228820
Description of:LY2228820
LY2228820 is a novel and potent p38MAPK inhibitor: in vitro kinase enzyme activity showed that the IC50 for p38α...
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CC-401
Description of:CC-401
CC-401 competitively binds the ATP binding site of JNK, resulting in inhibition of the phosphorylation of the N-ter...
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AS 602801
Description of:AS 602801
AS 602801(Bentamapimod) is a novel, orally active, Jun Kinase Inhibitor (JNK-I AS602801)
Theoretical analysis...
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AZ 628
Description of:AZ 628
AZ 628 is a selective RAF inhibitor. AZ 628 shows strong selectivity for RAF kinases among a panel of 150 tested kinases;...
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GW 5074
Description of:GW 5074
GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor (IC50 = 9 nM). GW 5074 displays ≥ 100-fold ...
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Antibody-drug Conjugate/ADC Related
MAP4K
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