常州市存仁生物工程有限公司

产品 > MAPK > p38 MAPK > VX745
产品名称 : VX745
型号 : CR1069
CAS : 209410-46-8
 放大                   返回
←[上一个产品]              [下一个产品]→


产品详细:
Description of:VX745
In vitro, VX-745 was selective for p38 MAPK compared to a large panel of kinases (IC50≥20µM). VX-745 selectively inhibited p38α MAPK (IC50=10 nM), p38β MAPK (IC50 =220 nM) [368149], but not p38γ MAPK (IC50≥20 µM). In addition, cell data for VX-745 provided IC50 values of 56 and 52 nM for IL-1β and TNFα, respectively, and VX-745 blocked IL-6 and IL-8 production induced by IL-1 and TNFα. In a human whole blood assay, IC50 values were 152 and 177 nM for IL-1β and TNFα inhibition, respectively.

Theoretical analysis:VX745
M.Wt:436.26
Formula:C19H9Cl2F2N3OS
Solubility:Soluble to 100 mM in DMSO
Purity:>98%
Storage:Store at -20°C
CAS No: 209410-46-8

Availability and price:VX745
Pakage:250mg/500mg/1g/5g
We offer significant discount for larger quantity order.
For quotation, question, and order, please send email to :
orders@chemrenblock.com

Quality control data:
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
Product will be shipped with supporting analytical data.
Fast delivery about 4-5 working days


相关产品 :
SB 202190
SB 202190
TAK715
TAK715
SB242235
SB242235
Doramapimod(BIRB 796)
Doramapimod(BIRB 796)
PH797804
PH797804
SB 239063
SB 239063
SB202190
SB202190
PD169316
PD169316