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Flavopiridol hydrochloride
Description of:Flavopiridol hydrochloride
Flavopiridol (at 7.5 mg/kg) significantly inhibited the growth of xenografted rhabdoid tumors, and it...
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SNS-032(BMS387032)
Description of:SNS-032(BMS387032)
SNS-032 (formerly BMS-387032) is a small-molecule cyclin-dependent kinase (CDK) inhibitor currently in phase ...
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AZD-5438
Description of:AZD-5438
AZD-5438 is a potent inhibitor of cyclin-dependent kinase (cdk) 1, 2 and 9 (IC50 values are 16, 6 and 20 nM respectivel...
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R547
Description of:R547
In vivo, R547 showed antitumor activity. The selective kinase inhibition profile and the preclinical antitumor activity of ...
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PHA-848125
Description of:PHA-848125
PHA-848125 can have a therapeutic potential in melanoma patients, alone or combined with TMZ. Moreover this agent app...
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Dinaciclib(Sch 727965)
Description of:Dinaciclib(Sch 727965)
SCH 727965 inhibits CDK2, CDK5, CDK1, and CDK9 activity in vitro with IC50 values of 1, 1, 3, and 4 nmol/...
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PHA-793887
Description of:PHA-793887
PHA-793887 is a novel pan-cdk inhibitor, including cdk1, cdk2, cdk4, cdk5, cdk7, and cdk9 with IC50 in the 5 to 140 n...
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CGP60474
Description of:CGP60474
CGP60474 is a potent inhibitor of cyclin-dependent kinase (CDK).
Theoretical analysis:CGP60474
M.Wt: 35...
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BS-181
Description of:BS-181
BS-181 is a selective cyclin-dependent kinase inhibitor with an IC50 of 21 nM for the inhibition of CDK-activating kinase...
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Roscovitine(CYC202)
Description of:Roscovitine
Roscovitine inhibits p34 cdc2/cyclin B (IC50 = 0.65 μM), p33 cdk2/cyclin A(IC50 = 0.70 μM), p33 cdk2/cyclin E ...
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Antibody-drug Conjugate/ADC Related
PERK
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