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产品名称 : Tenovin-1
型号 : CRT917
CAS : 380315-80-0
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产品详细:
Description of:Tenovin-1
Tenovin-1 is a small molecule activator of p53 transcriptional activity. At 10 µM, it elevates p53 expression in MCF-7 cells within two hours of treatment and longer-term exposure significantly decreases the growth of BL2 Burkitt’s lymphoma and ARN8 melanoma cells.1 Functioning upstream of p53, tenovin-1 acts by inhibiting the deacetylase activity of purified human SIRT1 and SIRT2, members of NAD+-dependent class III histone deacetylases that belong to the sirtuin family.1 While tenovin-1 demonstrates low genotoxicity, the compound has poor water solubility, which limits its uses in vivo.

Theoretical analysis:Tenovin-1
Formal Name N-​[[[4-​(acetylamino)phenyl]amino]thioxomethyl-​4-​(1,​1-​dimethylethyl)]-​benzamide
CAS Number 380315-80-0
Molecular Formula C20H23N3O2S
Formula Weight 369.5
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES CC(=O)​Nc1ccc(cc1)​NC(=S)​NC(=O)​c1ccc(cc1)​C(C)​(C)​C

Availability and price:Tenovin-1
Pakage:25mg/50mg/100mg/250mg/500mg/1g/5g
Stock : in stock
We offer significant discount for larger quantity order.
For quotation, question, and order, please send email to : sales@chemrenpharm.com

Quality control data:
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
Product will be shipped with supporting analytical data.
Fast delivery about 4-5 working days


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