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ALK5 INHIBITOR
Theoretical analysis:ALK5 INHIBITOR
Formula:C17H13N5
Solubility:Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:>99 %...
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INCB28060
Description of:INCB28060
Oral dosing of INCB28060 results in time- and dose-dependent inhibition of c-MET phosphorylation and tumor growth in c...
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BMS-599626
Description of:BMS-599626
BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the prolife...
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BIBF1120
Description of:BIBF1120
BIBF 1120 inhibits mitogen-activated protein kinase and Akt signaling pathways in three cell types contributing t...
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PCI-32765
Description of:PCI-32765
PCI-32765 is highly active and well tolerated in CLL/SLL pts irrespective of high risk genomic abnormalities. Although...
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SB-431542
Description of:SB-431542
SB-431542 is potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor acti...
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AEE788
Description of:AEE788
AEE788 demonstrated antiproliferative activity against a range of EGFR and ErbB2-overexpressing cell lines and inhibited ...
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OSI930
Description of:OSI 930
OSI-930 is designed to target both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors.<...
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Cediranib(AZD2171)
Description of:Cediranib (AZD2171)
Cediranib (AZD2171) is a once-daily oral tyrosine kinase inhibitor that targets vascular endothelial growth ...
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MP470
Description of:MP470
MP470 reduced c-Met phosphorylation and enhanced radiation-induced cell kill by 0.4 logs in SF767 cells. Cells pretr...
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Antibody-drug Conjugate/ADC Related
Trk Receptor
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