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奥拉帕尼|olaparib(AZD2281)

Description of:olaparib(AZD2281)奥拉帕尼
AZD2281(olaparib)shows activity in BRCA-1 deficient breast cancer cells. Cell-kill in the presence of the ...

Description of:ABT-888(Veliparib)
ABT-888 is a potent inhibitor of both PARP-1 and PARP-2 by [3H]NAD+ with Kis of 5.2 and 2.9 nmol/L, respectiv...

Description of:AG14361
It caused a >3-fold sensitization of PARP-1+/+ cells to topotecan compared with a <1.4-fold sensitization in PARP-...

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