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Products > Aurora/Ksp > Aurora > MLN8054
Product name : MLN8054
Item : CR1016
CAS : 869363-13-3
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Details:
Description of:MLN8054
Human tumor cells treated with MLN8054 show a high incidence of abnormal mitotic spindles, often with unseparated centrosomes.Auora kinase inhibitor MLN8054 binds to and inhibits Aurora kinase A, resulting in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregration, and inhibition of cell proliferation.MLN8054-treated cells frequently show alignment defects during metaphase, lagging chromosomes in anaphase, and chromatin bridges during telophase. 

Theoretical analysis:MLN8054
M.Wt:  476.86
Formula:  C25H15ClF2N4O2
Solubility:  Soluble in DMSO
Purity:  >99%
Storage:  -20C 2 years
CAS No:  869363-13-3 

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