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Products > HDAC > HDAC > AR-42 (HDAC-42)
Product name : AR-42 (HDAC-42)
Item : CR1135
CAS : 935881-37-1
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Details:

Description of:AR-42 (HDAC-42)
AR-42 produces dose- and time-dependent acetylation both of histones and tubulin, and induces caspase-dependent apoptosis that is not reduced in the presence of stromal cells. AR-42  significantly reduced leukocyte counts and/or prolonged survival in three separate mouse models of B-cell malignancy without evidence of toxicity. AR-42 has in vitro and in vivo efficacy at tolerable doses. In additon, AR-42 promoted hyperacetylation of H3, H4, and alpha-tubulin, and up-regulation of p21.


Theoretical analysis:AR-42 (HDAC-42)
M.Wt: 312.36
Formula: C18H20N2O3
Solubility: Unknown
Purity: >99%
Storage: at -20℃ 2 years
CAS No: 935881-37-1

Availability and price:AR-42 (HDAC-42)
Pakage:10mg/25mg/100mg/250mg/500mg/1g/5g
Stock : in stock
We offer significant discount for larger quantity order.
For quotation, question, and order, please send email to :
sales@chemrenpharm.com
Quality control data:
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
Product will be shipped with supporting analytical data.
Fast delivery about 4-5 working days


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