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Product name : IKKε-IN-1
Item : CR1078
CAS : 1292310-49-6
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Details:

Biological Activity of IKKε-IN-1

IKKε-IN-1 is a potent IKKε inhibitor; inhibit the in-situ ΙKΚ ε-mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM.

Chemical Information

M.Wt 457.52 Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Formula C26H27N5O3
CAS No 1292310-49-6
Solvent & Solubility

DMSO 21 mg/ml

Preparing Stock Solutions

1 mg 5 mg 10 mg
1 mM 2.1857 mL 10.9285 mL 21.8570 mL
5 mM 0.4371 mL 2.1857 mL 4.3714 mL
10 mM 0.2186 mL 1.0928 mL 2.1857 mL

References on IKKε-IN-1

 

[1]. Preparation of amino-pyrimidine compounds as inhibitors of TBK1 kinase and IKK kinase epsilon. From PCT Int. Appl. (2011), WO 2011046970 A1 20110421.
 


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