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Description of:PD98059
PD98059 is inhibitor of mitogen-activated protein kinase kinase (MAPKK / MEK). PD98059 acts by binding to the inactivated form of MEK, thereby preventing its phosphorylation by cRAF or MEK kinase (IC50 = 2-7 μM). PD98059 inhibits cell growth and proliferation in acute myelogenous leukemia (AML) cell lines; causes G1 arrest by blocking p53-dependent p21 induction. Theoretical analysis:PD98059 M.Wt:267.28 Formula:C16H13NO3 Solubility:Soluble to 25 mM in DMSO and to 5 mM in ethanol Purity:>99% Storage:Store at RT CAS No: 167869-21-8 Availability and price: Pakage:250mg/500mg/1g/5g We offer significant discount for larger quantity order. For quotation, question, and order, please send email to : sales@chemrenpharm.com Quality control data: Quality Control by H-NMR,C-NMR,LC-MS,HPLC. Product will be shipped with supporting analytical data. Fast delivery about 4-5 working days |
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