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产品 > MAPK > MEK > Selumetinib (AZD6244)司美替尼
产品名称 : Selumetinib (AZD6244)司美替尼
型号 : CR1045
CAS : 606143-52-6
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产品详细:

Description of:AZD6244
AZD6244 potently down-regulated the levels of phospho-ERK1/2 and its downstream effector, p-p70S6K, in the MV4-11 and MOLM13 cells as measured by Western blot analysis. Four BRAF mutant lines exhibited growth inhibition at low doses of the drug, with GI50 concentrations ranging from 14 to 50 nM, predominantly via a G0/G1 arrest, comparable with findings in a sensitive BRAF mutant melanoma cell line. 


Theoretical analysis:AZD6244
M.Wt: 457.68
Formula: C17H15BrClFN4O3
Solubility: 20 mmol/L in DMSO
Purity: 98%
Storage: -20C 2 years
CAS No: 606143-52-6

Availability and price:
Pakage:250mg/500mg/1g/5g
We offer significant discount for larger quantity order.
For quotation, question, and order, please send email to :
orders@chemrenblock.com

Quality control data:
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
Product will be shipped with supporting analytical data.
Fast delivery about 4-5 working days

若要询价或订购,请打销售电话咨询:0519-85788828,或加QQ:2500035664咨询,量大从优,我们会尽快回复。

注意事项:仅于科学研究和实验室使用。


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