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Description of:BAY 61-3606
BAY 61-3606 (BAY 61-3606) is a cell-permeable imidazopyrimidine compound that acts as a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki 7.5 nM) with no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. BAY 61-3606 has been shown to inhibit Syk-mediated cellular functions such as inhibition of high glucose-tyrosine phosphorylation of I kappa B α and p65 nuclear translocation. In mast cells BAY 61-3606 has inhibited cytokine synthesis, lipid mediation and degranulation Theoretical analysis:BAY 61-3606 M.Wt: 390.4 Formula: C20H18N6O3 Purity: >98% Storage: at -20℃ 2 years CAS No.: 732983-37-8 Solubility: DMSO Availability and price:BAY 61-3606 Pakage:25mg/50mg/100mg/250mg/500mg/1g/5g Stock : in stock We offer significant discount for larger quantity order. For quotation, question, and order, please send email to : sales@chemrenpharm.com Quality control data: Quality Control by H-NMR,C-NMR,LC-MS,HPLC. Product will be shipped with supporting analytical data. Fast delivery about 4-5 working days |
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