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产品 > 抑制剂 > > KRN633
产品名称 : KRN633
型号 : CR2019
CAS : 286370-15-8
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产品详细:

Biological Activity

Description KRN 633 is an ATP-competitive inhibitor of VEGFR1, 2 and 3 with IC50 values of 170 nM, 160 nM and 125 nM,respectively.
Targets VEGFR3 VEGFR2 VEGFR1      
IC50 125 nM 160 nM 170 nM      
Cas No. 286370-15-8 SDF Download SDF
Chemical Name 1-[2-chloro-4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-3-propylurea
Canonical SMILES CCCNC(=O)NC1=C(C=C(C=C1)OC2=NC=NC3=CC(=C(C=C32)OC)OC)Cl
Formula C20H21ClN4O4 M.Wt 416.86
Solubility Soluble in DMSO > 10 mM Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

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